| 武汉市HIV/AIDS病人合并乙肝、丙肝感染情况分析 |
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| 引用本文： | 刘薇1,刘建忠2,阮连国1,罗燕和1,刘莉1,张定宇1. 武汉市HIV/AIDS病人合并乙肝、丙肝感染情况分析[J]. 现代预防医学, 2020, 0(10): 1873-1875 |
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| 作者姓名： | 刘薇1 刘建忠2 阮连国1 罗燕和1 刘莉1 张定宇1 |
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| 作者单位： | 1.武汉市金银潭医院，湖北 武汉 430000；2.湖北省中医院，湖北 武汉 430061 |
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| 摘 要： | 目的 了解武汉市HIV/AIDS病人合并乙肝、丙肝感染情况及其相关因素。方法 在2010 - 2018年武汉市报告的确证HIV/AIDS病人中，选取其一般人口学特征、感染途径、HBsAg、AntiHCV检测结果等信息进行整理分析，采用多元logistic回归分析合并感染相关因素。结果 2010 - 2018年武汉市共报告HIV/AIDS病人5 128人，男4 630人（90.3%），女498人（9.7%）。年龄范围14～89岁，年龄中位数33（25～48）岁。其中，HBsAg阳性率为9.4%（443人），AntiHCV阳性率为3.3%（152人），合并HIV、HBV、HCV三重感染率为0.3%（12人）。在HIV/AIDS病人中，本省人群感染乙肝的可能性是本市人群的1.317倍，已婚/同居以及离异/分居/丧偶者感染乙肝的可能性分别是未婚者的2.044、1.892倍（P＜0.05）。与2018年相比，2011 - 2013以及2015年报告的HIV/AIDS病人感染丙肝的可能性更高，经输血和静脉吸毒途径感染的HIV/AIDS病人感染丙肝的可能性分别是经性行为传播者的18.942倍、63.537倍（P＜0.05）。结论 武汉市HIV/AIDS病人合并乙肝、丙肝感染情况不容忽视，其感染乙肝、丙肝的相关因素并不相同，需积极进行评估。
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| 关 键 词： | HIV/AIDS病人 乙肝病毒 丙肝病毒 合并感染 |
Seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among HIV/AIDS patients in Wuhan |
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| LIU Wei,LIU Jian-zhong,RUAN Lian-guo,LUO Yan-he,LIU Li,ZHANG Ding-yu. Seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among HIV/AIDS patients in Wuhan[J]. Modern Preventive Medicine, 2020, 0(10): 1873-1875 |
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| Authors: | LIU Wei LIU Jian-zhong RUAN Lian-guo LUO Yan-he LIU Li ZHANG Ding-yu |
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| Affiliation: | *Wuhan Jinyintan Hospital, Wuhan, Hubei 430000, China |
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| Abstract: | To explore seroprevalence of hepatitis B virus(HBV) and hepatitis C virus(HCV) among HIV/AIDS patients in Wuhan city and its associated factors. Methods Demographics, route of HIV infection, HBsAg and AntiHCV status of HIV/AIDS patients in Wuhan city during 2010-2018 were selected and analyzed. We used multivariate logistic regression to explore the associated factors. Results Totally 5128 HIV/AIDS patients were reported in Wuhan city during2010-2018, among which 4630 were males(90.3%) and 498 were females(9.7%). The age range was 14-89 years old, with a median age of 33(25-48) years. 443(9.4%) were HIV-HBV co-infected, 152(3.3%) were HIV-HCV co-infected and 12(0.3%) were HIV-HBV-HCV triple infection. Among HIV/AIDS patients, people who were living in Hubei province other than Wuhan city were more likely to infect HBV(OR=1.317,95%CI: 1.002-1.732), married/lived together(OR=2.044) and divorced/separated/widowed(OR=1.892) ones were more likely to infect HBV compared with unmarried(P<0.05). Compared with 2018, HIV/AIDS patients reported in 2011-2013 and 2015 were more likely to infect HCV. HIV/AIDS patients infected by blood transfusion and injected drugs had higher risk of infecting HCV compared to those infected by sexual transmission(OR=18.942, 95% CI: 3.987-90.005; OR =63.537, 95% CI: 34.948-115.511; respectively). Conclusion Prevalence and co-infection of HBV and HCV among HIV/AIDS patients in Wuhan city cannot be ignored. The associated factors of HBV and HCV infection are different, and active assessment is in need. |
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| Keywords: | HIV/AIDS patients HBV HCV Co-infection |
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