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韶关市健康人群百日咳、白喉和破伤风抗体水平监测
引用本文:黄辉,胡国超,邓俊兴.韶关市健康人群百日咳、白喉和破伤风抗体水平监测[J].疾病监测,2005,20(3):128-130.
作者姓名:黄辉  胡国超  邓俊兴
作者单位:1.广东省韶关市疾病预防控制中心 512026
摘    要:目的 了解韶关市健康人群百日咳、白喉和破伤风免疫状况,及时为免疫策略提供科学依据。方法 随机抽查部分0~4 0岁健康人群进行了百日咳、白喉和破伤风抗体水平监测。结果 百日咳抗体几何平均滴度GeimetricMeanTiter(GMT)和抗体保护率分别为1∶374 2、67.74% ;白喉、破伤风抗毒素GMT分别为0.1699IU/ml、0.1804IU/ml,阳性率分别为88.94 %、91.83%。结论 对百日咳、白喉和破伤风已经形成了较好的免疫屏障,但人群百日咳抗体水平偏低,应大力推广应用吸附无细胞百日咳、白喉、破伤风联合疫苗.

关 键 词:百日咳    白喉    破伤风    抗体水平
文章编号:1003-9961(2005)03-0128-02
收稿时间:2004-05-11
修稿时间:2004年5月11日

Monitoring on antibody levels of pertussis, diphtheria and tetanus in healthy population of Shaoguan
HUANG Hui,HU Guo-chao,DENG Jun-xing.Monitoring on antibody levels of pertussis, diphtheria and tetanus in healthy population of Shaoguan[J].Disease Surveillance,2005,20(3):128-130.
Authors:HUANG Hui  HU Guo-chao  DENG Jun-xing
Affiliation:1.Shaoguan Center for Disease Control and Prevention of Guangdong Province;Shaoguan 512026 China
Abstract:Objective This study was intended to understand the status of immunization against pertussis, diphtheria and tetanus in healthy population and provide a timely scientific basis for immunization strategy.Methods A number of healthy people aged between 0-40 were randomly selected to undergo monitoring antibody levels of pertussis, diphtheria and tetanus.Results The geometric mean titer (GMT) and rate of protection for pertussis antibody were 1:374.2 and 67.74%, respectively; GMT of diphtheria and tetanus antitoxin was 0.1699IU/ml and 0.1804IU/ml, with a positive rate of 88.94% and 91.83%, respectively.Conclusion A good immunological barrier against pertussis, diphtheria and tetanus has formed, but the antibody level of pertussis among people is a little lower, therefore we should strongly extend the use of Adsorbed Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine.
Keywords:Pertussis  Diphtheria  Tetanus  Antibody level
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