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3D培养在神经胶质瘤研究中的应用
引用本文:孙 慧,赵丽娇,鲁 静,巩 培,万 方. 3D培养在神经胶质瘤研究中的应用[J]. 现代肿瘤医学, 2019, 0(6): 1090-1094. DOI: 10.3969/j.issn.1672-4992.2019.06.046
作者姓名:孙 慧  赵丽娇  鲁 静  巩 培  万 方
作者单位:内蒙古农业大学,内蒙古 呼和浩特 010018
摘    要:
传统的肿瘤研究依赖于肿瘤细胞系构建肿瘤模型,并在细胞基础上测定肿瘤细胞的耐药性等,但在临床实验中大多数肿瘤药物以失败告终,其中最主要的原因是细胞系不能模拟肿瘤细胞在人体内微环境的特性,3D培养技术在肿瘤研究中的应用愈加广泛。本文主要从3D培养在神经胶质瘤研究中的应用进行综述。

关 键 词:3D培养  神经胶质瘤  肿瘤微环境

Application of 3D culture in glioblastoma research
Sun Hui,Zhao Lijiao,Lu Jing,Gong Pei,Wan Fang. Application of 3D culture in glioblastoma research[J]. Journal of Modern Oncology, 2019, 0(6): 1090-1094. DOI: 10.3969/j.issn.1672-4992.2019.06.046
Authors:Sun Hui  Zhao Lijiao  Lu Jing  Gong Pei  Wan Fang
Affiliation:Inner Mongolia Agriculture University,Inner Mongolia Hohhot 010018,China.
Abstract:
Traditional oncology research relies on tumor cell lines to construct tumor models,and it determines tumor cell resistance on the basis of cells.However,most of the oncology drugs have failed in clinical trials.The most important reason is that cell lines can' t simulate the characteristics of tumor cells in the human microenvironment,so the application of 3D culture technology in cancer research is more extensive.This article mainly introduces the application of 3D culture technology in glioblastoma research.
Keywords:3D culture   glioblastoma   tumor microenvironment
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