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Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies |
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| Authors: | Laperche Syria Saune Karine Dény Paul Duverlie Gilles Alain Sophie Chaix Marie-Laure Gaudy Catherine Lunel Françoise Pawlotsky Jean-Michel Payan Christopher Pozzetto Bruno Tamalet Catherine Thibault Vincent Vallet Sophie Bouchardeau Françoise Izopet Jacques Lefrère Jean-Jacques |
| Affiliation: | Institut National de la Transfusion Sanguine, 6 rue Alexandre-Cabanel, 75015 Paris, France. |
| Abstract: | A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide a reliable HCV genotype for clinical and epidemiological purposes as long as they are provided a consensus reference sequence database. |
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