| 植物代谢组学在根及根茎类中药材中的研究进展 |
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| 引用本文： | 杨钰颖,苗水,李雯婷,季申.植物代谢组学在根及根茎类中药材中的研究进展[J].中草药,2023,54(20):6856-6865. |
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| 作者姓名： | 杨钰颖 苗水 李雯婷 季申 |
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| 作者单位： | 上海中医药大学中药学院, 上海 201203;上海市食品药品检验研究院, 国家药品监督管理局中药质量控制重点实验室, 上海 201203 |
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| 基金项目： | 国家药典委员会课题（2022Z14）；上海市中药和保健食品品质与安全检测专业技术服务平台（21DZ2290200） |
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| 摘 要： | 随着生命科学研究的深入和仪器分析手段的进步，植物代谢组学作为一种重要的分析手段逐渐应用于根及根茎类中药材的研究。通过对植物代谢组学技术在根及根茎类中药品种鉴定、正常及外界因素影响下的种植生长及采收加工等方面的应用进行综述，为根及根茎类中药的亲缘种属鉴定、生长发育机制、炮制机制及质量安全控制等研究提供可靠依据，为其药效机制的深入挖掘、人工种植方法的改良、炮制方式的最佳选择、市售质量控制及安全性评价等方面的深入研究提供参考，使植物代谢组学技术在根及根茎类中药全产业链发展中能够更好的发挥其作用。
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| 关 键 词： | 植物代谢组学 根 根茎 中药 代谢产物 检测技术 |
| 收稿时间： | 2023/4/25 0:00:00 |
Research progress on plant metabolomics in root and rhizome traditional Chinese medicine |
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| YANG Yu-ying,MIAO Shui,LI Wen-ting,JI Shen.Research progress on plant metabolomics in root and rhizome traditional Chinese medicine[J].Chinese Traditional and Herbal Drugs,2023,54(20):6856-6865. |
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| Authors: | YANG Yu-ying MIAO Shui LI Wen-ting JI Shen |
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| Affiliation: | School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Key Laboratory for Quality Control of Traditional Chinese Medicine of National Medical Products Administration, Shanghai Institute for Food and Drug Control, Shanghai 201203, China |
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| Abstract: | With the advancement of life science research and instrumental analysis, plant metabolomics has been gradually applied to the study of root and rhizome herbs as an important analytical tool. The paper reviews the application of plant metabolomics technology in the identification of root and rhizome Chinese medicine species, cultivation and growth under the influence of normal and external factors as well as harvesting and processing, with the aim of providing a reliable basis for research on the identification of related species, growth and development mechanism, preparation mechanism and quality and safety control of root and rhizome traditional Chinese medicine, and providing references for the in-depth research on the mechanism of medicinal efficacy, improvement of artificial cultivation method, optimal selection of preparation method, quality control of marketing and safety evaluation, so that the plant metabolomics technology can better play its role in the development of the whole industrial chain of root and rhizome traditional Chinese medicine. |
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| Keywords: | plant metabolomics roots rhizomes traditional Chinese medicine metabolite detection technology |
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