| 武汉市丙肝病例调查及疫情控制策略探讨 |
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| 引用本文： | 马红飞,王夏,周旺,刘聪,董全林,刘普林.武汉市丙肝病例调查及疫情控制策略探讨[J].现代预防医学,2019,0(6):1109-1111. |
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| 作者姓名： | 马红飞 王夏 周旺 刘聪 董全林 刘普林 |
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| 作者单位： | 武汉市疾病预防控制中心，湖北 武汉 430015 |
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| 摘 要： | 目的 调查武汉市医院丙型病毒性肝炎（简称丙肝）报告病例，探讨丙肝疫情控制策略。方法 采用分层随机抽样方法选取武汉市6家医院作为调查单位，对2017年4月-2018年3月期间诊断并报告的丙肝病例进行问卷调查，并进行统计学分析。结果 本研究共调查272例新发丙肝报告病例，男女比例为2.18∶1，平均年龄为（53.41±13.50）岁。病人因医疗服务前筛查、转氨酶升高和急性丙肝症状进行HCV感染检测的比例分别为67.65%、63.60%和13.24%，病人主动要求检测或因体检进行HCV感染检测的比例为23.16%。病例中，78.68%无高危行为，11.03%曾接受过血液或血制品，8.46%曾进行过不安全注射、共用针具吸毒或街边店美容纹身等操作。丙肝病例诊断类型的正确率为94.12%。病例中，29.00%天冬氨酸氨基转移酶/血小板比值指数（APRI）＞2。确诊病例中本次选择抗病毒治疗的比例为25.81%，其中90.00%为小分子药物抗病毒治疗。结论 有针对性地开展丙肝防制工作，促进丙肝病例早发现、早诊断和早治疗，有助于控制丙肝疫情的发展。
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| 关 键 词： | 丙型病毒性肝炎 病例调查 疫情控制 |
Investigation and analysis of viral hepatitis C cases in hospitals of Wuhan and exploration on epidemic control strategies |
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| MA Hong-fei,WANG Xia,ZHOU Wang,LIU Cong,DONG Quan-lin,LIU Pu-lin.Investigation and analysis of viral hepatitis C cases in hospitals of Wuhan and exploration on epidemic control strategies[J].Modern Preventive Medicine,2019,0(6):1109-1111. |
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| Authors: | MA Hong-fei WANG Xia ZHOU Wang LIU Cong DONG Quan-lin LIU Pu-lin |
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| Affiliation: | Wuhan Center for Disease Prevention and Control, Wuhan,Hubei 430015, China |
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| Abstract: | Objective To investigate the reported cases of viral hepatitis C(HCV) in hospitals of Wuhan, and to explore epidemic control strategies. Methods 6 hospitals of Wuhan were selected by stratified random sampling method,HCV cases diagnosed and reported between April 2017 and March 2018 were investigated by questionnaires, and data was analyzed statistically. Results A total of 272 of newly reported HCV cases were investigated in this study. The male and female ratio was 2.18:1, the average age was 53.41±13.50 years. HCV infection testing due to pre-medical screening, transaminase elevation and acute HCV infection symptoms accounted for 67.65%, 63.60% and 13.24%, respectively. The proportion of patients who conducted HCV infection tests out of their own willingness and those who did it in physical examination was 23.16%. Among these cases, 78.68% had no history of high-risk behaviors, 11.03% had history of blood transfusion, and 8.46% had history of unsafe injections, needle sharing drug use or street side store tattooing and other invasive operations. The accuracy rate of HCV diagnostic type of these hospitals was 94.12%. And 29.00% of all the cases had an Aspartate aminotransferase-to-platelet ratio index (APRI) higher than 2. Of all the confirmed HCV infection cases, the ratio of antiviral treatment was 25.81%, among which 90.00% were direct-acting antiviral agents(DAAs) treatment. Conclusion HCV prevention and control measurements should be conducted pertinently, which can promote early detection, early diagnosis and early treatment of HCV infection cases and help control the epidemic of HCV. |
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| Keywords: | Viral hepatitis C Case investigation Epidemic control |
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