| 甲状腺癌淋巴结转移的相关因素分析 |
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| 引用本文： | 齐子蛟,刘良发.甲状腺癌淋巴结转移的相关因素分析[J].国际耳鼻咽喉头颈外科杂志,2017,41(1):30. |
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| 作者姓名： | 齐子蛟 刘良发 |
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| 作者单位： | 首都医科大学附属北京友谊医院耳鼻咽喉头颈外科,北京,100050 |
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| 摘 要： | 甲状腺癌（thyroid carcinoma）是最常见的甲状腺恶性肿瘤，来源于甲状腺上皮细胞，以甲状腺乳头状癌（papillary thyroid carcinoma，PTC）最为好发。如果治疗得当，预后良好；但也存在一定的复发率。甲状腺癌复发是影响患者预后及生存质量的重要因素，PTC患者约30%~80%发生区域性淋巴结转移，而淋巴结转移是引起肿瘤复发的主要因素，且甲状腺癌颈部淋巴结的转移逐渐成为评价预后的重要影响因素，因此术前诊断是否有颈淋巴结转移尤为重要。目前甲状腺癌术前检查包括B超、增强CT及细针穿刺抽吸细胞学检查（fine-needle aspiration cytology，FNAC），有助于提高颈淋巴转移的诊断率，但每项检查均有其局限性，处于转移早期的淋巴结或淋巴结肿大不明显者，难以做出准确判断。如果能够发现与淋巴结转移相关的临床因素，这对手术方式的选择及指导术后治疗具有重要意义。现对目前国内外研究从临床特点、辅助检查及分子生物学方面进行总结与分析。
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| 关 键 词： | 甲状腺肿瘤 淋巴结转移 |
Related risk factors of cervical lymph node metastasis in thyroid carcinoma |
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| Qi Zijiao,Liu Liangfa.Related risk factors of cervical lymph node metastasis in thyroid carcinoma[J].International Journal of Otolaryngology-Head and Neck Surgery,2017,41(1):30. |
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| Authors: | Qi Zijiao Liu Liangfa |
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| Abstract: | Thyroid carcinoma is the most common thyroid cancer,derived from thyroid epithelial cells,among which papillary thyroid carcinoma (PTC) is most frequent.If treated properly,the prognosis is very well;but there is certain recurrence rate.Thyroid carcinoma recurrence is one of the important factors which affect prognosis and the quality of life.About 30％～80％ of PTC patients undergo regional lymph node metastasis (LNM) and LNM easily causes tumor recurrence.At present,ultrasound,enhanced CT and FANC,areused to diaqnose LNM before opration,but each examination has its limitations.In the early stage of LNM,it is difficult to make accurate judgment.Now we research to reveal the relationship between LNM and examination features,clinicopathologic characteristics and molecular biology. |
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| Keywords: | Thyroid Neoplasms lymph node metastasis |
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