Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis – case report and review of the literature |
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| Authors: | Dita Ricna Martina Lengerova Martina Palackova Marketa Hadrabova Iva Kocmanova Barbora Weinbergerova Zdenek Pavlovsky Pavlina Volfova Jana Bouchnerova Jiri Mayer Zdenek Racil |
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| Affiliation: | 1. Department of Internal Medicine – Hematology and Oncology, University Hospital Brno, Brno, Czech Republic;2. Faculty of Medicine, Masaryk University, Brno, Czech Republic;3. CEITEC – Central European Institute of Technology, Masaryk University, Brno, Czech Republic;4. Department of Clinical Microbiology, University Hospital Brno, Brno, Czech Republic;5. Department of Pathology, University Hospital Brno, Brno, Czech Republic |
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| Abstract: | Disseminated fusariosis is a life‐threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus, with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts. |
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| Keywords: |
Fusarium proliferatum
fusariosis PCR diagnostics real‐time PCR |
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