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支气管镜介入治疗10例儿童获得性声门下狭窄的临床观察
引用本文:张光莉,王崇杰,彭帅,谷瑞雪,谢晓虹,罗健,罗征秀.支气管镜介入治疗10例儿童获得性声门下狭窄的临床观察[J].四川大学学报(医学版),2022,53(1):166-170.
作者姓名:张光莉  王崇杰  彭帅  谷瑞雪  谢晓虹  罗健  罗征秀
作者单位:重庆医科大学附属儿童医院 呼吸科 国家儿童健康与疾病临床医学研究中心 儿童发育疾病教育部重点实验室 儿科学重庆市重点实验室 (重庆 400014)
基金项目:国家临床重点专科建设项目(No. 2011-873)资助
摘    要:目的 探讨支气管镜介入治疗儿童获得性声门下狭窄(subglottic stenosis,SGS)的临床疗效.方法 回顾性分析2019年1月–2020年12月重庆医科大学附属儿童医院收治的10例获得性SGS患儿临床资料,以及治疗后1周、1个月、3个月和6个月的随访资料.观察经支气管镜介入治疗(包括球囊扩张、钬激光、冷冻等...

关 键 词:获得性声门下狭窄  介入治疗  支气管镜术  儿童
收稿时间:2021-05-28

The Effect of Interventional Treatment with Bronchoscopy in 10 Children with Acquired Subglottic Stenosis
ZHANG Guang-li,WANG Chong-jie,PENG Shuai,GU Rui-xue,XIE Xiao-hong,LUO Jian,LUO Zheng-xiu.The Effect of Interventional Treatment with Bronchoscopy in 10 Children with Acquired Subglottic Stenosis[J].Journal of West China University of Medical Sciences,2022,53(1):166-170.
Authors:ZHANG Guang-li  WANG Chong-jie  PENG Shuai  GU Rui-xue  XIE Xiao-hong  LUO Jian  LUO Zheng-xiu
Affiliation:Department of Respiratory Medicine, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Key Laboratory of Child Development and Disorders of the Ministry of Education, and Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China
Abstract:  Objective  To explore the effects of interventional therapy with bronchoscopy in children with acquired subglottic stenosis (SGS).   Methods  The clinical data of ten pediatric inpatients with acquired SGS who were admitted to Children’s Hospital of Chongqing Medical University, as well as their follow-up information obtained 1 week, 1 month, 3 months and 6 months after the procedure was done.were retrospectively analyzed to examine the effect of interventional bronchoscopic therapies, including balloon dilatation, holmium laser, and cryotherapy, in pediatric patients with acquired SGS.  Results  Among the 10 patients with acquired SGS, there were 5 boys and 5 girls aged between 1 month and 6 years and 5 months, with a median age of 11 months and 1 day. Among the 5 patients with acute acquired SGS, two were treated with balloon dilatation only, with one cured and one showing clinical improvement, while three received comprehensive interventional therapy combining balloon dilatation, holmium laser, and cryotherapy, with two cured and one showing improvement. Among the 5 patients with chronic acquired SGS, four cases were cured with comprehensive interventional therapy, while one case suffered from aggravated upper airway obstruction 4+ hours after balloon dilatation. The patient was subsequently put on invasive mechanical ventilation for 4 days, but was unable to be extubated. The parents signed do-not-resuscitate order and the patient died afterwards. Bronchoscopy performed 1 week, 1 month and 3 months after the procedure was done showed that the SGS was improved to varying degrees.  Conclusion  Bronchoscopy intervention is an effective therapy for acquired SGS in children.
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