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Failure of Phorbol Myristate Acetate to Damage DNA in Leukocytes from Patients with Chronic Granulomatous Disease
Authors:H. C. Birnboim and W. D. Biggar
Affiliation:1Atomic Energy of Canada Limited, Chalk River Nuclear Laboratories, Chalk River, Ontario K0J IJ0, Canada;2Department of Pediatrics, Research Institute, The Hospital for Sick Children and University of Toronto, Toronto, Ontario M5G IX8, Canada
Abstract:
Unlike leukocytes from normal donors, leukocytes from patients with chronic granulomatous disease do not suffer DNA damage on exposure to the tumor promoter, phorbol myristate acetate.
Keywords:
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