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The selective ROCK2 inhibitor KD025 reduces IL‐17 secretion in human peripheral blood mononuclear cells independent of IL‐1 and IL‐6
Authors:Isak W. Tengesdal  David Kitzenberg  Suzhao Li  Melanie S. Nyuydzefe  Wei Chen  Jonathan M. Weiss  Jingya Zhang  Samuel D. Waksal  Alexandra Zanin‐Zhorov  Charles A. Dinarello
Affiliation:1. Dept. Medicine, University of Colorado Denver, Aurora, CO, USA;2. Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands;3. Kadmon Corporation, LLC, New York, NY, USA
Abstract:
Keywords:Candida albicans  Human PBMCs  Pro‐Inflammatory Cytokine IL‐17  ROCK2  Staphylococcus epidermidis
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