| 肝脏缺血再灌注损伤与细胞凋亡 |
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| 作者姓名： | 马毅 何晓顺 陈规划 |
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| 作者单位： | 1.中山大学附属第一医院器官移植中心,广东,广州,510080 |
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| 基金项目： | 卫生部临床学科重点项目(No.97040230);广东省科委攻关基金(No.99M04902G) |
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| 摘 要： | Hepatic ischemia/reperfusion injury (HIRI) exists in lots of process of clinical pathology and operation. Apoptosis is an active process controlled by some gene and factors such as Fas/FasL, Caspases and Bcl -2 families. More and more studies suggest that HIRI is associated with apoptosis. This article summarized the mechanisms and gene modulation of apoptosis during HIRI and the significance of suppressing auoutosis in preventing HIRI.
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| 关 键 词： | 细胞凋亡 再灌注损伤 基因 肝 |
| 文章编号： | 1000-4718(2003)07-1005-04 |
| 收稿时间： | 2002-11-07 |
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