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| 13例线状IgA大疱性皮病临床病理特征分析 | |
| 引用本文： | 邱云,迪丽努尔·阿布都热依木,梁俊琴,吴曹英,毛丽旦,康晓静. 13例线状IgA大疱性皮病临床病理特征分析[J]. 中国麻风皮肤病杂志, 2021, 37(8): 510-514. DOI: 10.12144/zgmfskin202108510 |
| 作者姓名： | 邱云 迪丽努尔·阿布都热依木 梁俊琴 吴曹英 毛丽旦 康晓静 |
| 作者单位： | 新疆维吾尔自治区人民医院，新疆皮肤病研究重点实验室（XJYS1707）,乌鲁木齐,830001 |
| 摘 要： | 收集2012年7月至2019年6月在本科室诊治的13例LABD,其中男11例,女2例.儿童型6例,成人7例.临床表现:红斑基础上或外观正常的皮肤上出现水疱和大疱,疱壁紧张,疱液清亮,尼氏征(-).皮损组织病理均见表皮下疱,直接免疫荧光见IgA线状沉积于基底膜带.1例患者合并类风湿关节炎,1例患者合并器质性焦虑障碍,1例... |
| 关 键 词： | 线状IgA大疱性皮病 自身免疫性疱病 |
Clinicopathological analysis of 13 cases of linear IgA bullous dermatosis |
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| QIU Yun,Dilinuer·Abudureyimu,LIANG Junqin,WU Caoying,MAO Lidan,KANG Xiaojing. Clinicopathological analysis of 13 cases of linear IgA bullous dermatosis[J]. China Journal of Leprosy and Skin Diseases, 2021, 37(8): 510-514. DOI: 10.12144/zgmfskin202108510 | |
| Authors: | QIU Yun Dilinuer·Abudureyimu LIANG Junqin WU Caoying MAO Lidan KANG Xiaojing |
| Affiliation: | People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research (XJYS1707), Urumqi 830001, China |
| Abstract: | The data of 13 patients including 11 males and 2 females with linear IgA bullous dermatosis (LABD) in our hospital from July 2012 to June 2019 were analyzed. There were 6 children and 7 adults in the group. The manifestations were blisters and bullae appeared on the erythema or on the normal skin. The blisters were tense with negative Nikosky's sign. Histological examination showed subepidermal blisters in all lesions. Direct immunofluorescence showed linear deposited of IgA in basement membrane. Each of five patient was complicated with rheumatoid arthritis, organic anxiety disorder, paroxysmal nocturnal hemoglobinuria, hypoproteinemia and chronic hepatitis B, respectively. |
| Keywords: | linear IgA bullous dermatosis autoimmune bullous disease |
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