Irritable bowel syndrome in Asia: Pathogenesis,natural history,epidemiology, and management |
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| Authors: | Kok‐Ann Gwee Uday Chand Ghoshal Minhu Chen |
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| Affiliation: | 1. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;2. Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India;3. Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat‐Sen University, Guangzhou, China |
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| Abstract: | Historically, the epidemiology of gastrointestinal diseases in Asia was different from that in Western countries. Early studies suggested a low prevalence of irritable bowel syndrome (IBS) in Asia. As the diagnosis of IBS is symptom‐based and as symptom perception, expression, and interpretation are influenced by sociocultural perspectives including language, the presentation of IBS is expected to vary in different communities. Furthermore, the pathogenesis is multifactorial with psychosocial (stress, illness, behavior, and diet) and biological (infection, gut microbiota, and immune activation) variables interacting, and so, the present study can anticipate that the development of IBS will vary in different environments. In recognition of this aspect of functional gastrointestinal disorders, the recently published Rome IV documents have provided greater focus on cross‐cultural factors. In this review, the present study seeks to highlight Asian perspectives by identifying historical trends and recent publications from the region and comparing these with the observations from Western societies. |
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| Keywords: | abdominal pain antispasmodics Asia bloating cross‐cultural research diet irritable bowel syndrome Rome criteria |
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