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香加皮不同入药方式的杠柳毒苷提取率比较研究
引用本文:杨虹,刘虹,孙巍,王萌,高秀梅. 香加皮不同入药方式的杠柳毒苷提取率比较研究[J]. 天津中医药大学学报, 2007, 24(1): 71-72
作者姓名:杨虹  刘虹  孙巍  王萌  高秀梅
基金项目:天津市高等学校科技发展基金项目(20050310);天津市卫生局中医、中西医结合科研基金(2005072)。
摘    要:[目的] 比较不同入药方式香加皮中杠柳毒苷提取率,为香加皮药材入药方式的选择及临床用药的安全性提供参考。[方法] 采用不同入药方式(传统水煎煮、回流提取、浸渍提取)提取香加皮,采用高效液相色谱(HPLC)法测定,Hypersil ODS色谱柱(4.6mm×250mm,5µm),流动相为乙腈-水(27:73),流速1.0mL/min,检测波长220nm。计算提取的杠柳毒苷总量和提取率。[结果] 3种方法的提取率依次为57.84%、95.01%、99.85%。[结论] 应该关注不同入药方式引起的杠柳毒苷提取量问题。

关 键 词:香加皮  杠柳毒苷  提取率
收稿时间:2006-10-20

Comparison of extracted ratio of periplocin in cortex periplocae with different extracting manner
YANG Hong,LIU Hong,SUN Wei. Comparison of extracted ratio of periplocin in cortex periplocae with different extracting manner[J]. Journal of Tianjin University of Traditonal Chinese Medicine, 2007, 24(1): 71-72
Authors:YANG Hong  LIU Hong  SUN Wei
Abstract:[Objective] To compare the extracted ratio of periplocin in Cortex Periplocae with different extracting manner.[Methods] Cortex Periplocae was extracted with different extracting manner (traditional decocting,refluxing or and macerating method).Extracted amount of periplocin was determined by HPLC and extracting ratio was calculated.[Results] The extracted ratios of these three methods were 57.84%,95.01%,99.85% respectively.[Conclusions] It should be noted that different extracting method can obtain different extracted amount of periplocin.
Keywords:cortex periplocae  periplocin  extracted ratio
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