Abstract: Through the research and analysis of Chinese medicine master Zhou Zhongying's records of the differentiation and treatment of coronary heart disease， it is summarized that the syndrome differentiation of coronary heart disease by professor Zhou is established on compound pathogenesis and the treatment with a view to composite prescription. By listing common compound pathogenesis of the differentiation and treatment of coronary heart disease by professor Zhou， evidence can be given that the differentiation and treatment of coronary disease is aimed at the pathogenesis including deficiency of qi and yin， stagnation of heart ying， failure in spread of chest yang， retention of phlegm and stasis， etc.