Humoralism is the most basic and important Uygur medicine theory, which found that many complexity disease is often caused by abnormal savda. There is high incidence and certain clinical characteristic in XinJiang, such as Uygur, Kazak. Uygur medicine theory has formed a unique differentiation diagnosis methods and characteristics of the formulas for these complexity diseases in the longterm medical practice. The team was headed by professor Hamulati·WUFUER who took on many national projects, the team carried out indepth study with the support of these projects. This paper is mainly summarized the main research results.