Objective: To observe treatment effects of Jiawei Sancai Fengsuitang on eukopenia after chemotherapy. Method: Eighty-nine patients ientered treatment group. Treatment group was treated with oral Jiawei Sancai Fengsuitang, daily; The control group was treated with oral 20 mg of leucogen and batyl alcohol 100 mg three times daily, times. Result: Treatment group increased the clinical curative effect, white leukocyte count and physical state after treatment were superior to control. So it showed statistically significant (P<0.01). Intercurrent infection and chemotherapy were lower than those of the control group, and it has statistical differences (P<0.05). Adverse reactions were not found in the treatment group. Conclusion: Jiawei Sancai Fengsuitang can improve the physical state and immunological functions, and can reduce infection and chemotherapy delay rate.