[关键词]
[摘要]
目的 阐明兰科石斛属植物细叶石斛Dendrobium hancockii的化学成分。方法 采用各种柱色谱及制备液相色谱分离纯化,经波谱数据鉴定结构。结果 从细叶石斛中分离得到9个化合物,其结构分别鉴定为3,α-二羟基-4,5,3'-三甲氧基联苄(1)、4,3',5'-三羟基-3-甲氧基联苄(2)、4,4'-二羟基-3,5,3'-三甲氧基联苄(3)、4,3'-二羟基-3,5'-二甲氧基联苄(4)、7-羟基-2-甲氧基-1,4-菲醌(5)、2,5-二羟基-4-甲氧基菲(6)、2,5-二羟基-4,9-二甲氧基菲(7)、nobilone(8)和crepidatuol B(9)。结论 化合物1为新化合物,命名为细叶石斛酚A;其余化合物均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from Dendrobium hancockii. Methods The compounds were isolated and purified by column chromatography and preparative HPLC, and their structures were elucidated by spectral analysis. Results A total of nine compounds were isolated from D. hancockii and the structures were identified as 3,α-dihydroxy-4,5,3'-trimethoxybibenzyl (1), 3,4',5-trihydroxy-3-methoxybibenzyl (2), 4,4'-dihydroxy-3,5,3'-trimenthoxybibenzyl (3), 4,3'-dihydroxy-3,5'-dimethoxybibenzyl (4), 7-hydroxy-2-methoxy-1,4-phenanthrenequinone (5), 2,5-dihydroxy-4-methoxyphenanthrene (6), 2,5-dihydroxy-4,9-dimethoxyphenanthrene (7), nobilone (8), and crepidatuol B (9). Conclusion Compound 1 is a new compound named dendrohanol A, and compounds 2-9 are isolated from this plant for the first time.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(31560102);贵州省教育厅自然科学研究项目(黔教合KY字[2015]362)